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EAY191 – E4

Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial

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EAY191 – S3 (JIT)

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

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• All Trial Categories Anal  (4) Bladder/Urinary Tract Cancer  (5)    Metastatic  (2)    Neoadjuvant  (2) Brain  (8)    Glioblastoma Multiforme (GBM)  (2)    Other Brain Tumors  (3) Breast  (9)    Breast Cancer Adjuvant  (2) Cancer Control/Symptom Management  (26) Carcinoid Tumors  (2) Colorectal Cancer  (8)    Metastatic  (2)    Rectal Neoadjuvant  (1) Esophageal Cancer  (3) Gall Bladder/ Biliary Tract Cancer  (2) Gastric Cancer  (2) Head/Neck Cancer  (8) Leukemia  (1)    Acute Myeloid Leukemia (AML)  (1) Lung Cancer  (22)    Non-Small Cell Lung Cancer  (17)       1st Line Metastatic, Stage3b with Maligned Effusion or Stage 4 Disease at Presentation or Recurrence  (2)       2nd Line Metastatic, Stage 4 Patients with Progressive Disease  (1)       Adjuvant Treatment for Resected NSCLC  (4)    Small Cell Lung Cancer  (7)       Extensive Stage SCLC  (3) Lymphoma  (1)    Non-Hodgkin’s Lymphoma  (1) MDS  (1) Melanoma  (4) Merkel Cell Carcinoma  (3) Misc. Gynecology  (3) Multiple Myeloma  (3) Ovarian  (1) Pancreatic  (7)    Metastatic Disease  (2) Prostate  (10) Renal Cell/Kidney Cancer  (3)    Locally Advanced/Metastatic  (2) Sarcoma  (3)